Radiation Oncology - Deformable PET Fusion

PET Edge Tool


Deformed PET/CT Alignment Improves GTV Definition

Take the Guesswork out of PET Contouring

Deformable PET fusion allows PET/CT's, even those not obtained in treatment position, to be more accurately aligned to the planning CT¹, an essential step in the accurate contouring of target volumes.

MIM provides automatic PET contouring tools, including PET Edge, an innovative gradient-based segmentation method for more accurate tumor delineation. PET Edge has been shown to provide more accurate and consistent segmentations than SUV thresholds or manual contouring ^2-5.

Key features

• utilize PET/CT effectively even when not in treatment position
• deformably register PET/CT to planning CT for improved alignment accuracy
• overcome non-rigid positioning differences
• define GTV accurately with MIM's PET segmentation method, PET Edge

1. Fogh SE, Kubicek GJ, Axelrod R, Keane WM, Piper JW, Xiao Y, Machtay M. Utility of Deformable PET Fusion Gross Tumor Volumes in Head & Neck Malignancies. Presented at ASTRO Translational Advances in Radiation Oncology and Cancer Imaging 2008 Poster Presentation.
2. Fogh S, Karancke J, Nelson AS, McCue P, Axelrod R, Werner-Wasik W. Pathologic Correlation of PET-CT Based Auto-contouring for Radiation Planning in Lung Cancer. Presentation at the World Conference on Lung Cancer Meeting 2009.
3. Nelson D, et al. PET Tumor Segmentation: Multi-observer Validation of a Gradient-based Method Using a NSCLC PET Phantom. Accepted for Presentation at the ASTRO Annual Meeting 2009.
4. Nelson AD, Brockway KD, Nelson AS, Piper JW. PET Tumor Segmentation: Validation of a Gradient-based Method Using a NSCLC PET Phantom. J Nucl Med. 2009; 50 (Supplement 2):1659
5. Shen G, Nelson D, Adler L. PET Tumor Segmentation: Comparison of Gradient-Based Algorithm to Constant Threshold Algorithm. Medical Physics June 2007; 34(6): 2395.